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NECROSIS OF ALVEOLAR BONE BY FORMOCRESOL CASE REPORT

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¹Úöȫ ( Park Cheol-Hong ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
À̳­¿µ ( Lee Nan-Young ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
ÀÌâ¼· ( Lee Chang-Seep ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
ÀÌ»óÈ£ ( Lee Sang-Ho ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç

Abstract

À¯Ä¡ÀÇ Ä¡¼öÀý´Ü¼ú¿¡ »ç¿ëµÇ´Â ¾àÁ¦·Î´Â formocresol, ferric sulfate, ¼ö»êÈ­Ä®½· µîÀÌ ÀÖ´Ù.

±× Áß¿¡¼­ formocresolÀº Ä¡¼öÁ¶Á÷ÀÇ °íÁ¤´É·Â°ú ³ôÀº ÀÓ»óÀû ¼º°øÀ» º¸ÀÓÀ¸·Î½á ¾ÆÁ÷±îÁö ³Î¸® »ç¿ëµÇ°í ÀÖÀ¸³ª ÀÚüµ¶¼ºÀÌ ¸Å¿ì °­ÇÏ¿© ¿µ±¸ °è½ÂÄ¡ Ä¡¹èÀÇ º¯À§³ª °á¼Õ, ¹ý¶ûÁú Çü¼ººÎÀü, Àü½Å Èí¼ö·Î ÀÎÇÑ µ¹¿¬º¯ÀÌ °¡´É¼º°ú ¾ÏÀ¯¹ß °¡´É¼º ¿ª½Ã º¸°íµÇ°í ÀÖ´Ù. ÃÖ±Ù¿¡´Â formocresolÀÇ ±Ù°ü³» Àû¿ë½Ã ºÒ¿ÏÀüÇÑ ÀÓ½ÃÃæÀü¿¡ ÀÇÇÑ ¹Ì¼¼´©Ãâ·Î ÁÖÀ§ Ä¡Àº°ú Ä¡Á¶°ñÀÇ ±«»ç¸¦ ¾ß±âÇÑ º¸°í°¡ ÀÖÀ¸¸ç, °úÀ×ÀÇ formocresolÀ» Àû¿ëÇÏ¿´À» °æ¿ì¿¡µµ Ä¡Á¶°ñÀÇ ±«»çÀÇ ¿øÀÎÀÌ µÉ ¼ö ÀÖ´Ù°í ÇÏ¿´´Ù.

º» Áõ·Ê´Â °³ÀÎÄ¡°ú¿¡¼­ formocresolÀ» ÀÌ¿ëÇÑ Ä¡¼öÄ¡·á¸¦ ¹ÞÀº ÈÄ Áö¼ÓµÇ´Â µ¿ÅëÀ¸·Î ÀÎÇØ »ó¾Ç ÁÂÃø Á¦ 2À¯±¸Ä¡¸¦ ¹ß°ÅÇÏ¿´À¸³ª. Áõ»óÀÌ °³¼±µÇÁö ¾Ê¾Æ º»¿ø¿¡ ÀǷڵǾú´Ù. ȯ¾Æ´Â 8¼¼ ³²¾Æ·Î ½ÉÇÑ ±¸Ãë ¹× °è½Â ¿µ±¸Ä¡ Ä¡°ü ÁÖÀ§·Î ȯÇüÀÇ Ä¡Á¶°ñ ±«»ç¸¦ º¸¿© ºÎ°ñÀýÁ¦¼úÀ» ½ÃÇàÇÏ°í 1³â 7°³¿ù°£ °üÂûÀ» ÇÏ¿´À» ¶§. Á¤»óÀûÀÎ Ä¡±Ù ¼ºÀåÀº ÀÌ·ç¾îÁ³À¸³ª °á¼ÕµÈ Ä¡Á¶°ñ ¹× ºÎÂøÄ¡ÀºÀÇ ¿ÏÀüÇÑ Á¶Á÷Àç»ý ¼Ò°ßÀº °üÂûµÇÁö ¾Ê¾Ò´Ù.

Formocresol¿¡ ÀÇÇÑ Ä¡ÁÖÁ¶Á÷¿¡ ´ëÇÑ ºÎÀÛ¿ëÀº ºñ°¡¿ªÀûÀ̹ǷΠformocresolÀÇ »ç¿ë¿¡ ÀÖ¾î ÀûÀÀÁõ ¿©ºÎ¸¦ Àß ÆÇ´ÜÇؾßÇϸç, öÀúÇÑ Àӽà °¡ºÀ¿¡ ÁÖÀǸ¦ ±â¿ï¿©¾ß ÇÒ °ÍÀÌ´Ù.

Various chemotherapeutic agents have been recommended for pulpotomy of primary teeth, and there are formocresol, ferric sulfate, and calcium hydroxide.

Of those, formocresol has fixation effect of pulp tissue and high clinical success rate, so it is most commonly used agent. But formocresol has strong cytotoxic effects, thus many articles reported displacement and loss of permanent successor, amelogenesis imperfecta, mutation by general absorption, possibility of cancer induction. Recently, it has been reported that leakage by imperfect temporary sealing when FC-soaked cotton was inserted into the root canal caused necrosis of surrounding tissues, and that necrosis of alveloar bone related to the use of excessive formocresol.

In this case, 2nd primary molar of upper left jaw was treated using formocresol in local clinic, but extracted because of lasting pain, Furthermore, symptoms didn¡¯t disappear, so patient was refered to us. The patient was 8-year-old male, had foul oder from oral cavity and circular alveolar bone necrosis around the permanent successor crown. Thus sequestrectomy was operated and observed through 19 months after operation, we found normal root development of permanent successor but no complete regeneration of alveolar bone defect and attached gingiva.

Lesion of periodontal tissues by formocresol is irrelversible, so we have to confirm the indication in using formocresol and pay attention to complete temporary sealing.

Å°¿öµå

Formocresol;Ä¡Á¶°ñ ±«»ç;À¯±¸Ä¡;ºÎ°ñÀýÁ¦¼ú
Formocresol;Alveolar bone necrosis;Primary molar;Sequestrectomy

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